Best friend problems

I know my best friend is not feeling well, I can feel that.
But I also know that whenever she's feeling not good you have to take a step back, because she doesn't like help, but sometimes you have to open up for help right?

So do I have to help her or not?
I don't want to be in a fight with her because she's really sweet.
But she can't have everything for herself...
Help me!